Evaluating functions of praise for children diagnosed with autism spectrum disorder.

We assessed whether novel praise statements could be used to (a) maintain and increase responses with existing reinforcement histories and (b) teach a previously untaught response among children diagnosed with autism spectrum disorder across two experiments. During response-stimulus pairing, two responses resulted in preferred edibles but only one also produced a praise statement. In the absence of edibles, the response continuing to produce praise tended to persist more. Next, reversing the praise contingency tended to increase the other response. However, in no case did contingent delivery of those same praise statements result in the acquisition of untaught responses. These findings suggest that conditioning praise statements could serve different functions (antecedent or consequence) depending on the reinforcement history for particular responses.

Research and mentorship in behavior analysis from a lens of cultural responsiveness and antiracism.

Although scientific endeavors strive to be objective, they are the work of individuals whose unique perspectives and experiences influence their research and interpretations of the world and data. Much has been said and written lately about the need to embed cultural responsiveness in behavior analysis and the need to enhance diversity in the field. In fact, similar conversations are taking place in many areas of science. Despite the current buzz, many behavioral researchers may be left wondering what they can do or whether it is incumbent on them to act. For the field of behavior analysis to move toward adopting the values of diversity, equity, inclusion, and access, members of the scientific community must actively engage in behaviors that foster inclusive and safe learning environments for students, engage in collaborative work, and incorporate culturally responsive research and mentorship practices. This article will describe some current practices, showcase exemplars of culturally responsive research and mentorship, and provide resources for researchers and mentors.

Effects of pay rate and instructions on attrition in crowdsourcing research.

Researchers in social sciences increasingly rely on crowdsourcing marketplaces such as Amazon Mechanical Turk (MTurk) and Prolific to facilitate rapid, low-cost data collection from large samples. However, crowdsourcing suffers from high attrition, threatening the validity of crowdsourced studies. Separate studies have demonstrated that (1) higher pay rates and (2) additional instructions-i.e., informing participants about task requirements, asking for personal information, and describing the negative impact of attrition on research quality-can reduce attrition rates with MTurk participants. The present study extended research on these possible remedies for attrition to Prolific, another crowdsourcing marketplace with strict requirements for participant pay. We randomly assigned 225 participants to one of four groups. Across groups, we evaluated effects of pay rates commensurate with or double the US minimum wage, expanding the upper range of this independent variable; two groups also received additional instructions. Higher pay reduced attrition and correlated with more accurate performance on experimental tasks but we observed no effect of additional instructions. Overall, our findings suggest that effects of increased pay on attrition generalize to higher minimum pay rates and across crowdsourcing platforms. In contrast, effects of additional instructions might not generalize across task durations, task types, or crowdsourcing platforms.

Isolated and Stressed? Examining the Effects of Management Communication in Alleviating Mental Health Symptoms during COVID-19.

The goal of this research was to assess the role of professional isolation on mental health symptoms via stress among employees working remotely due to COVID-19. Additionally, this research explored the interactive effect of management communication on the relationship between professional isolation and stress, and stress and mental health symptoms. In Study 1, behavior analysts who were working remotely as a result of the pandemic completed assessments of professional isolation, stress, and mental health symptoms at two points in time, separated by two weeks. Study 2 replicated and extended the findings from Study 1 in a sample of remote employees recruited from Amazon's Mechanical Turk using a three-wave design. Findings of both Study 1 and Study 2 suggested that stress mediated the relationship between professional isolation and mental health symptoms. Additionally, management communication buffered the association between stress and mental health symptoms in Study 2. Lastly, the indirect effect of professional isolation on mental health symptoms was stronger for those who received less communication from their management. The findings of these two studies expand our understanding of the mechanism and boundary condition through which professional isolation is related to mental health symptoms.

Cultural responsiveness in applied behavior analysis: Research and practice.

The new Ethics Code for Behavior Analysts requires that certificants engage in training related to culturally responsive service delivery (BACB, 2020). There is limited work in the area of culturally responsive evidence-based practice within our field. Therefore, it is incumbent on researchers and practitioners to identify best practices for working with diverse populations. Hence, the purpose of this paper is three-fold: a) to review research within and outside the field of ABA related to culturally responsive assessment and treatment and provide practice recommendations, b) to examine the extent to which current practices in behavior assessment and treatment align with aspects of culturally responsive practices, and c) to inspire research in the areas of behavior assessment and treatment to identify best practices with regard to culturally responsive behavior analytic practices. The content of this paper is grounded in the framework described by Beaulieu and Jimenez-Gomez (2022).

Cultural responsiveness in applied behavior analysis: Self-assessment.

Culture has a substantial impact on a wide range of behaviors related to behavioral research and services such as rapport building, preferences for specific targets and treatments, communication, and even the quality of health care. The need for professionals in the field of applied behavior analysis (ABA) to incorporate culturally responsive practices is underscored by the current and projected increase in diversity in the United States. Further, the update to the Ethics Code (BACB, 2020) supports addressing diversity in behavior analytic practice. Self-assessment of one's values, biases, and culture are a critical step in delivering culturally responsive services. The purpose of this paper is three-fold: a) to introduce a framework for cultural responsiveness in ABA, b) to showcase research and practice recommendations from within and outside the field of ABA in the area of self-assessment, and c) to inspire research in self-assessment to support cultural responsiveness in ABA.

Impact of COVID-19 on the Applied Behavior Analysis Workforce: Comparison across Remote and Nonremote Workers.

With the abrupt transition to observing physical distancing as a result of COVID-19, applied behavior analysts were faced with the sudden need to modify their service delivery model, while at the same time managing personal difficulties brought about by the pandemic. The present article provides a description of the impact of COVID-19 on the behavior analyst workforce currently providing clinical services in the United States. We conducted a survey to assess work conditions, burnout, and productivity of behavior analysts at various certification levels. These data provide a snapshot of the impact of COVID-19 on the workforce. Overall, one third of the participants reported experiencing job insecurity, and almost half of participants reported decreased productivity and increased burnout, with remote workers more severely affected. Taken together, these factors could compromise the ability of behavior analysts to adequately provide services to their clients. We provide recommendations for behavioral health agencies for supporting staff during extreme situations such as a pandemic.

Wearable activity schedules to promote independence in young children.

Activity schedules consist of a series of visual discriminative stimuli, arranged in booklets or binders, which function as prompts for appropriate behavior. Although activity schedules are useful, their typical presentation in binders can be cumbersome and stigmatizing, placing additional barriers for independence and inclusion. The purpose of the present studies was to evaluate the usefulness of a wearable activity schedule and determine whether prompts provided by it would be sufficient to support completion of a complex chain of behaviors by young children. In Experiment 1, the Octopus watch® provided prompts to children of typical development to complete a morning routine independently. In Experiment 2, the usefulness of the watch was evaluated in children with autism spectrum disorder engaged in play activities in a clinical setting. In both experiments, children reliably displayed a greater proportion of independent engagement in target behaviors when prompts were delivered by the watch compared to control conditions.

Examining stimuli paired with alternative reinforcement to mitigate resurgence in children diagnosed with autism spectrum disorder and pigeons.

In two laboratory experiments, we examined whether stimuli paired with alternative reinforcers could mitigate resurgence of a previously reinforced target response with pigeons (Experiment 1) and children diagnosed with Autism Spectrum Disorder (Experiment 2). In Phase 1, we arranged food reinforcement according to a variable-ratio schedule for engaging in a target response. In Phase 2, we arranged extinction for target responding and differentially reinforced alternative responding according to a fixed-ratio schedule, with every alternative-reinforcer delivery paired with a change in keylight color (Experiment 1) or automated verbal (praise) statement (Experiment 2). In Phase 3, we assessed resurgence during extinction of target and alternative responding in the presence versus absence of continued presentation of the paired stimulus. Despite variation across sessions, resurgence on average was lower when continuing to present the paired stimuli in all pigeons and children while maintenance of alternative responding did not differ between assessments. These findings indicate that stimuli paired with alternative reinforcement can modestly decrease resurgence, but further examination of their efficacy and a better understanding of the underlying processes are necessary before they can be recommended for clinical use in reducing resurgence of clinically relevant problem behavior.

Resurgence is greater following a return to the training context than remaining in the extinction context.

The present study examined whether resurgence of a previously reinforced target response upon removing alternative reinforcement would be greater when (1) returning to the original training context (ABA context changes) versus (2) remaining in the analogue treatment context in which the alternative response was differentially reinforced (ABB context changes). Experiment 1 arranged reinforcement of button pressing with points exchangeable for money in university students. Experiment 2 arranged reinforcement of lever pressing with food for rats. Experiment 3 arranged reinforcement of responses to a touchscreen with small bites of food with children diagnosed with ASD. Overall, resurgence of target responding tended to be greater when returning to the original training context (A) than when remaining in the analogue treatment context (B). These findings suggest context changes with differential reinforcement treatments could exacerbate the recurrence of problem behavior resulting from reductions in treatment integrity through failure to reinforce appropriate behavior.

Matrix Training for Expanding the Communication of Toddlers and Preschoolers With Autism Spectrum Disorder.

Children diagnosed with autism spectrum disorder (ASD) typically exhibit a range of social communication deficits. Presequenced stimulus arrangements, such as matrix training, can be used to facilitate generative responding. Accordingly, training procedures can lead to the acquisition of a greater number of targets that are not taught explicitly, with fewer learning trials. Matrix training provides a useful framework for selecting teaching targets to promote the emergence of untaught skills. Participants were 3 young boys diagnosed with ASD, who were taught noun-verb combinations of play actions as tact and listener responses. All participants learned the taught noun-verb targets and showed varying degrees of recombinative generalization to untaught targets. Across subsequent matrices, the rate of acquisition of new targets and the number acquired without direct teaching increased (i.e., recombinative generalization). This suggests matrix training stimulus arrangements can facilitate the acquisition of novel targets by teaching young children with ASD to recombine language components appropriately.

Renewed behavior produced by context change and its implications for treatment maintenance: A review.

Behavioral treatment gains established in one setting do not always maintain in other settings. The present review examines the relevance of basic and translational research to understanding failures to maintain treatment gains across settings. Specifically, studies of the renewal effect examine how transitioning away from a treatment setting could evoke a return of undesirable behavior, rather than newly trained appropriate behavior. Studies of renewal typically arrange three phases, with a response trained and reinforced under a particular set of contextual stimuli in the first phase. Next, that response is extinguished, often under a different set of contextual stimuli. Finally, that response returns despite extinction remaining in effect upon returning to the original training context or transitioning to a novel context. Thus, removing the extinction context is sufficient to produce a recurrence of the response. The findings suggest treatment effects can become specific to the context in which the treatment was delivered. This literature offers promising methods for systematically assessing the factors contributing to treatment maintenance and improving generalization of treatment gains across contexts. Therefore, the present review suggests basic and translational research on renewal provides an empirical literature to bring greater conceptual systematization to understanding generalization and maintenance of behavioral treatment.

Contrafreeloading, reinforcement rate, and behavioral momentum.

Contrafreeloading involves organisms working for food when an identical source of food is freely available. The present study assessed whether training reinforcement rates influenced contrafreeloading by arranging a within-subject and within-session design using pigeons. Across different alternating discriminative stimuli, variable-interval schedules arranged leaner (30 per hour) and richer (120 per hour) rates of food reinforcement. Responding decreased but persisted in the presence of free food during the session (i.e., contrafreeloading). Further, responding tended to be similar between components initially but greater persistence emerged in the richer component with additional exposure. With pre-session feeding, responding did not change systematically across test sessions and tended to be more persistent in the richer component. Greater persistence with greater training reinforcement rates is generally consistent with an influential theory of response persistence, behavioral momentum theory. However, the different patterns of responding across test sessions between pre- and within-session feeding reveals multiple behavioral processes involved in contrafreeloading that have yet to be fully understood. Behavioral momentum theory could provide a useful theoretical framework for understanding and quantifying the behavioral processes underlying contrafreeloading.

Selectively promiscuous opioid ligands: discovery of high affinity/low efficacy opioid ligands with substantial nociceptin opioid peptide receptor affinity.

Emerging clinical and preclinical evidence suggests that a compound displaying high affinity for µ, κ, and δ opioid (MOP, KOP, and DOP) receptors and antagonist activity at each, coupled with moderate affinity and efficacy at nociceptin opioid peptide (NOP) receptors will have utility as a relapse prevention agent for multiple types of drug abuse. Members of the orvinol family of opioid ligands have the desired affinity profile but have typically displayed substantial efficacy at MOP and or KOP receptors. In this study it is shown that a phenyl ring analogue (1d) of buprenorphine displays the desired profile in vitro with high, nonselective affinity for the MOP, KOP, and DOP receptors coupled with moderate affinity for NOP receptors. In vivo, 1d lacked any opioid agonist activity and was an antagonist of both the MOP receptor agonist morphine and the KOP receptor agonist ethylketocyclazocine, confirming the desired opioid receptor profile in vivo.

Punishing and cardiovascular effects of intravenous histamine in rats: pharmacological selectivity.

Although drugs may serve as reinforcers or punishers of operant behavior, the punishing function has received much less experimental attention than the reinforcing function. A sensitive method for studying drug-induced punishment is to assess choice for a punished response over an unpunished response. In these experiments, rats chose between pressing one lever and receiving a sucrose pellet or pressing another lever and receiving a sucrose pellet plus an intravenous injection of histamine. When sucrose was delivered equally frequently for either the punished or the unpunished response, rats selected the unpunished lever consistently, but decreases in the punished response did not differ as a function of intravenous histamine dose (0.1-1 mg/kg/inj). Changing the procedure so that sucrose was delivered on the unpunished lever with p = .5 increased the rats' responding on the punished lever with saline injections. In addition, the same range of histamine doses produced a much larger range of responses on the punished lever that was dose dependent. Using these procedures to assess the receptors mediating histamine's effects, the histamine H1 -receptor antagonists, pyrilamine and ketotifen, antagonized the punishing effect of histamine, but the histamine H2 -receptor antagonist ranitidine did not. However, ranitidine pretreatments reduced histamine-induced heart-rate increases to a greater extent than did the histamine H1 -receptor antagonists when administered at the same doses examined under conditions of histamine punishment. Overall, the present findings extend the general hypothesis that activation of histamine H1 -receptors mediates the punishing effects of histamine. They also introduce methods for rapidly assessing pharmacological mechanisms underlying drug-induced punishment.

Are preference and resistance to change convergent expressions of stimulus value?

Behavioral momentum theory asserts that preference and relative resistance to disruption depend on reinforcement rates and provide converging expressions of the conditioned value of discriminative stimuli. However, preference and resistance to disruption diverge when assessing preference during brief extinction probes. We expanded upon this opposing relation by arranging target stimuli signaling equal variable-interval schedules across components of a multiple schedule. We paired one target stimulus with a richer reinforced alternative and the other with a leaner alternative. Furthermore, we varied reinforcement rates for the paired alternatives to assess the effects of manipulating relative conditioned value on preference and resistance to disruption by presession feeding, intercomponent food, and extinction. We replicated the opposing relation between preference and resistance to disruption but varying reinforcement rates for the paired alternatives did not systematically affect preference or resistance to disruption beyond levels observed in our initial condition. Importantly, we found that only preference between the target stimuli was related to relative baseline response rates in the presence of those stimuli. These findings suggest that preference during extinction probes might reveal more about baseline response rates between concurrently available alternatives than relative conditioned value. Resistance to disruption, conversely, appears to better reflect conditioned value because it is less confounded with baseline response rates and is a function of all sources of reinforcement obtained in the presence of a stimulus context.

Concurrent-chains schedules as a method to study choice between alcohol-associated conditioned reinforcers.

An extensive body of research using concurrent-chains schedules of reinforcement has shown that choice for one of two differentially valued food-associated stimuli is dependent upon the overall temporal context in which those stimuli are embedded. The present experiments examined whether the concurrent chains procedure was useful for the study of behavior maintained by alcohol and alcohol-associated stimuli. In Experiment 1, rats responded on concurrent-chains schedules with equal variable-interval (VI) 10-s schedules in the initial links. Across conditions, fixed-interval schedules in the terminal links were varied to yield 1∶1, 9∶1, and 1∶9 ratios of alcohol delivery. Initial-link response rates reflected changes in terminal-link schedules, with greater relative responding in the rich terminal link. In Experiment 2, terminal-link schedules remained constant with a 9∶1 ratio of alcohol delivery rates while the length of two equal duration initial-link schedules was varied. Preference for the rich terminal link was less extreme when initial links were longer (i.e., the initial-link effect), as has been previously reported with food reinforcers. This result suggests that the conditioned reinforcing value of an alcohol-associated stimulus depends on the temporal context in which it is embedded. The concurrent-chains procedure and quantitative models of concurrent chains performance may provide a useful framework within which to study how contextual variables modulate preference for drug-associated conditioned reinforcers.

Pharmacological evaluation of the adequacy of marble burying as an animal model of compulsion and/or anxiety.

Marble-burying behavior in rodents has been used commonly as an animal model of compulsive and/or anxiety behavior. The purpose of this study was to further assess the adequacy of marble burying as a preclinical animal model of compulsive behaviors using pharmacological tools. In particular, we were interested in whether dopamine D2/D3 agonists (e.g. pramipexole) known to produce compulsive behaviors in humans would increase marble burying. The effects of pramipexole on marble-burying behavior and locomotor activity were compared with those of the following: diazepam, a drug known to decrease marble burying; D-amphetamine, a stimulant that increases locomotor activity; and methyl ß-carboline-3-carboxylate, a ß-carboline previously shown to produce anxiogenic effects in rodents. All drugs produced dose-dependent decreases in marble burying, which were not always related to the locomotor effects of these drugs. The inability of pramipexole and methyl ß-carboline-3-carboxylate to increase marble burying questions the validity of this assay as an adequate animal model of compulsive and/or anxiety behavior.

Temporal context, preference, and resistance to change.

According to behavioral momentum theory, preference and relative resistance to change in concurrent-chains schedules are correlated and reflect the relative conditioned value of discriminative stimuli. In the present study, we explore the generality of this relation by manipulating the temporal context within a concurrent-chains procedure through changes in the duration of the initial links. Consistent with previous findings, preference for a richer terminal link was less extreme with longer initial links across three experiments with pigeons. In Experiment 1, relative resistance to change and preference were related inversely when responding was disrupted with response-independent food presentations during initial links, replicating a previous finding with rats. However, more food was presented with longer initial links, confounding the disrupter and initial-link duration. In Experiment 2, presession feeding was used instead and eliminated the negative relation between relative resistance to change and preference, but relative resistance to change was not sensitive to relative terminal-link reinforcement rates. In Experiment 3, with more extreme relative terminal-link reinforcement rates, increasing initial-link duration similarly decreased preference and relative resistance to change for the richer terminal link. Thus, when conditions of disruption are equal and assessed under the appropriate reinforcement conditions, changes in temporal context impact relative resistance to change and preference similarly.

Naltrexone decreases D-amphetamine and ethanol self-administration in rhesus monkeys.

Amphetamines are the second most highly abused illicit drugs worldwide, yet there is no pharmacological treatment for amphetamine abuse and dependence. Preclinical studies and, more recently, human studies, suggest that the opioid receptor antagonist, naltrexone, might be useful in the treatment of amphetamine abuse. Naltrexone, an opioid receptor antagonist, is currently used for the treatment of alcohol dependence. The aim of this study was to explore the ability of naltrexone to modify self-administration of amphetamine or ethanol in rhesus monkeys. Monkeys were trained to respond to intravenous injections of either D-amphetamine (0.003 mg/kg/injection) or ethanol (0.05 g/kg/injection) on a fixed ratio 30 schedule. Naltrexone (0.01-1 mg/kg) was administered intramuscularly 30 min before the start of treatment test sessions. Naltrexone dose-dependently decreased both amphetamine and ethanol self-administration. These findings support the potential use of naltrexone as therapy for amphetamine and polydrug abuse.